A needle-free peptide serum that softens the look of expression lines, the creases that form from repeated movements like frowning and smiling.

It pairs wrinkle-smoothing peptides (short chains of amino acids that signal skin) led by acetyl hexapeptide-8 with niacinamide (vitamin B3, which strengthens the moisture barrier) and gluconolactone, a gentle polyhydroxy acid that refines texture. SkinCeuticals reports visibly smoother skin and more radiance within a week.

Apply morning and night before moisturizer; in the daytime, layer it after a vitamin C serum and under sunscreen. It suits all skin types, including sensitive, and is designed to be used on its own or alongside neuromodulator injections (treatments such as Botox or Dysport that relax expression muscles).

Size: 30 mL
Best for: all skin types, including sensitive; expression lines and dull, uneven texture
Use: AM and PM, after serums and before moisturizer
Pairs well with: vitamin C, sunscreen, and in-clinic neuromodulator treatments